Global Remote Neurosurgical Research Collaborative

Advancing Evidence-Based
Neurosurgery

A global research collaborative producing high-quality evidence in cerebrovascular neurosurgery, neurotrauma, and spine — through systematic reviews, meta-analyses, and methodological research, conducted under the mentorship of Brandon Lucke-Wold, MD, PhD.

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15+
Active Members
10+
Current Projects
100+
Publications
10+
High-Impact Publications
About the Lab

Evidence synthesis in cerebrovascular neurosurgery, neurotrauma, and spine

The Lucke-Wold Neurosurgical Evidence Lab focuses its current research activities on cerebrovascular neurosurgery, neurotrauma, and spine. We conduct systematic reviews, meta-analyses, and methodological research within these domains — translating the global literature into evidence that guides clinical practice, while training the next generation of physician-researchers.

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Research Focus

Our Research Focus

The Lab's current research activities are organized around three primary domains.

01

Cerebrovascular Neurosurgery

Aneurysms, arteriovenous malformations, stroke, subarachnoid and intracerebral hemorrhage, neuroendovascular therapeutics, and neurovascular outcomes.

02

Neurotrauma

Traumatic brain injury, spinal trauma, trauma-related neurocritical care, injury mechanisms, and outcomes research.

03

Spine

Spinal trauma, degenerative spine disorders, spine surgery, and surgical-outcomes evidence synthesis.

Research Methods & Approaches

Our research uses systematic reviews, meta-analyses, evidence synthesis, methodological research, and quantitative approaches across our three primary domains: cerebrovascular neurosurgery, neurotrauma, and spine.

Systematic Reviews Meta-Analysis Evidence Synthesis AI in Medicine
Projects

Current focus

TAAF grant feature: Chadwin Hanna and Brandon Lucke-Wold
Recently Awarded

TAAF Grant: Bioresorbable Closed-Basket Flow Diverter with Therapeutic Microbubbles for Targeted Vascular Drug Delivery

Brandon Lucke-Wold, MD, PhD, together with Chadwin Hanna, has been awarded a TAAF grant to develop a next-generation dissolvable stent for brain aneurysms and AVMs that redirects dangerous blood flow and delivers targeted healing medication directly to damaged vessels using ultrasound — aiming for safer treatments, fewer complications, and better long-term outcomes for patients.

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Fluorescence-Guided Glioma Surgery

5-ALA vs. SWIG resection technique comparison.

Neurointerventional Biologics

Emerging biologic adjuncts in endovascular practice.

AI Reporting Standards

TRIPOD-LLM adherence in neurosurgical literature.

CNS Tumor Therapeutics

GLP-1 receptor agonists and emerging molecular targets.

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Team
Brandon Lucke-Wold
Faculty Director

Brandon Lucke-Wold, MD, PhD

Faculty Director, Lucke-Wold Neurosurgical Evidence Lab · Assistant Professor of Neurosurgery, University of Arizona — mentoring a distributed team of student researchers across systematic review, meta-analysis, and clinical methodology projects.

Meet the team
Mission
Our mission is to advance evidence-based neurosurgery by conducting methodologically rigorous systematic reviews, meta-analyses, and evidence synthesis in cerebrovascular neurosurgery, neurotrauma, and spine.
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Research Platform & Website Disclaimer

This website is an academic and research platform. It does not provide medical advice, diagnosis, treatment, or patient-specific clinical consultation. Please do not submit protected health information through this public website.

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